Monthly Archives: January 2021

A Sardinian founder mutation in glycoprotein Ib platelet subunit beta (GP1BB) that impacts thrombocytopenia

Posted on January 29, 2021 by Francesca Crobu
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Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease

Posted on January 26, 2021 by Francesca Crobu

The only cure for celiac disease is lifelong adherence to a strict gluten–free diet. IRGB Researchers and collaborators of the University of Groningen have identified a master regulator gene that is a potential drug target for an alternative cure.

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Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.

Posted on January 21, 2021 by Francesca Crobu
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Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids.

Posted on January 18, 2021 by mslmrc66
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