Giuseppina Casu obtained her degree of Biomedical Laboratory Technician at the University of Sassari in 1994, at present she works as technical assistant at the IRGB-CNR since 1996. Her research has almost always focused on the study of multifactorial diseases (kidney stones, hypertension) in isolated Sardinian Populations. Since 2008 to 2018, following an agreement between the IRGB and the Veterinary Physiology Institute of the University of Sassari, she participated in the project concerning the enhancement and conservation of the goat heritage in Sardinia. Furthermore, in the meantime she also collaborated to a study focusing on thalassemia in Vietnam.  

Her activities were based on the application of the main molecular biology techniques, such as: DNA extraction, with the saline method and with the Qiagen Kit, amplification of DNA with PCR, DNA sequencing with the ABI PRISM 3130 XL Genetic Analyzer automatic sequencer and DNA fragmentation with restriction endonucleases.   

Since 2020 she works on the detection and quantization of genetic mutations of DNA extracted from paraffin-embedded tumor tissue of cholangiocarcinoma and thyroid patients using the technique of Pyrosequencing with the PyroMark Q24 Qiagen version 2.0.6.